3D-QSAR Studies of Isatin Derivatives with Anti-Cancer In Vitro: Advanced CoMFA, CoMSIA and Docking Methods
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چکیده
منابع مشابه
CoMFA and CoMSIA 3D-QSAR analysis of DMDP derivatives as anti-cancer agents
Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) based on three dimensional quantitative structure-activity relationship (3D-QSAR) studies were conducted on a series (78 compounds) of 2, 4-diamino-5-methyl-5-deazapteridine (DMDP) derivatives as potent anticancer agents. The best prediction were obtained with a CoMFA standard model (q(2)...
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ژورنال
عنوان ژورنال: Chemical Sciences Journal
سال: 2017
ISSN: 2150-3494
DOI: 10.4172/2150-3494.1000158